However, the main finding of this study is not that more people suffer from allergies. That is already an accepted observation. Who owns them, who doesn’t. The author, immunologist David Strachan (David Strachan) reported that they were 20 years old at the time, and they conducted a lifelong study of British children born in 1958, if they were to be with their older brothers. When the sisters grow up together, it seems unlikely that they will develop hay fever. This means that older compatriots (who would have left home, go to school, and run outdoors with friends when the toddler returns home) will expose their young children to what they bring home under. This is a phenomenon that the eldest or only child cannot obtain. In this original study, the incidence of hay fever was higher than that of younger siblings.
The possibility of early contact something Preventing later troubles is intuitively appealing and has led to a series of studies linking allergies, eczema, and asthma to modern hygiene.Many observational studies report that in people who spend their childhood, allergies and asthma are less likely external The city that was put in Daycare Still a baby pet Or ever improve on farmIn general, it is concluded that for growing children, the messy and dirty pre-modern life is healthier.
This led to backlash, that parents desperately avoid allergies. Ignore Basic cleanliness Reframe Hygiene issue.Version 2.0 developed by Rook in 2003He believes that the allergen is not a lack of infection, but deprivation of contact with environmental organisms, and these environmental organisms have been our evolutionary companions for thousands of years. Rook calls this the “old friend” hypothesis, which suggests that exposure to these organisms allows our immune system to understand the difference between pathogens and offensive companions.
At the same time as this rethinking, laboratory science is acquiring the tools to characterize the microbiome, the membranes of these microbiomes, bacteria and fungi that occupy the inner and outer surfaces of everything in the world, including us. This helps expose the children (animals, other children, feces, dander, and dust) in these observational studies to animals, not as an infectious threat, but to keep their microbiota together with a variety of organisms Opportunity.
This knowledge in turn led to version 3.0, the hygienic hypothesis that now exists. Renamed the hypothesis of “disappearing microbiota”, Re-enactment By microbiologist Stanley Falkow (died in 2018) and physician researcher Martin J. It also warned that due to the effects of antibiotics, preservatives, poor diet and other threats , Our microbial diversity is drying up, so there is a lack of protection.
Take a quick look at the debate about lack of contact, namely childhood infections, Environmental bacteriaAnd other opportunities to replenish the diversity of microorganisms-to make the immune system out of balance with its surrounding environment. Although proponents of various versions may disagree on the details, today’s ideas have been widely accepted by pediatrics and immunology. But when we stand out from the fight against Covid-19, what does this mean for our immune system? This assumption cannot say exactly what will happen, because so far, researchers have only obtained data on the incidence of viral infections, and no other types of exposure data. However, these data are enlightening.
According to the CDC, in the southern hemisphere, where the flu season overlaps with the summer in the northern hemisphere, there will be “almost no flu transmission” in 2020. report In September.The agency has not yet released a final report on the flu experience in the United States this winter, but the World Health Organization Reported Last month, it has remained “below the baseline” throughout the northern hemisphere.